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I am developing experimental designs to understand far from equilibrium cellular processes. For more details on all the fun projects, research goals and collaborations of our group please check out Prof. Atul N Parikhs webpage! Microscopy (advanced as well as standard) and microfluidics are the core tools for most of our experiments. Feel free to get in touch if you would like to work with us!

HOW MEMBRANE COMPOSITION CREATE REVERSIBLE RESPONSE

ARTICLE HIGHLIGHTED IN BIOPHYSICAL JOURNAL

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SELECT RESEARCH PUBLICATIONS

Interplay between permeability and phase boundary forces mediate osmotic response of giant vesicles reconstituting plant lipids.

Shiva Emamia, Wan-Chih Su, Sowmya Purushothaman,Viviane N. Ngassamd, Atul N. Parikh*

Accepted in Biophysical Journal (2018).

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5.

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Dependence of norfloxacin diffusion across bilayers on lipid composition.

Sowmya Purushothaman, Jehangir Cama and Ulrich F. Keyser*.

Soft Matter, 12, (2016).

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4.

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The influence of high pressure on the bending rigidity of model membranes.

S. Purushothaman, Pietro Cicuta, Nick Brooks* and Oscar Ces.

Journal Physical Chemistry B, 119 (30), (2015).

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2.

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Measurements of the effect of membrane asymmetry on the mechanical properties of lipid bilayers.

S. Purushothaman*, Yuval Elani, Paula J. Booth and Oscar Ces*.

Chemical Communications, 5, (2015).

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Automated laboratory based X-ray beamline with multi-capillary sample chamber.

S. Purushothaman, B. L. L. E. Gauthe, N. J. Brooks, R. H. Templer*, O. Ces*.

Review of Scientific Instruments, 84 (2013).

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Driving a wedge: Topological interactions of conical amphiphiles promotes lateral phase separation and drives domain-induced budding in giant vesicles.

Douglas L.Gettel, JeremySanborn, Wan−ChihSu, Sowmya Purushothaman, Darryl Y. Sasaki, Atul N. Parikh** In Preparation.

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6.

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Membrane Biointerfaces: Active, Dynamic, and Adaptive Boundaries of Cellular Compartments.

Sowmya Purushothaman,Wan Chih Su, Shiva Emami, Atul N. Parikh* In Preparation

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Drug
Breamline
High pressure
Asymmetry
Plant

LIST OF PAST AND PRESENT COLLABORATORS

Prof. Atul N Parikh, UC Davis California, USA.

Prof. Mikkel Jensen, Sacremento State, USA.

Prof. Namjoon Cho, NTU Singapore, Singapore.

Prof. Ulrich Keyser, Cambridge University, UK.

Prof. Oscar Ces, Imperial College London, UK.

Prof. J M Seddon, Imperial College London, UK. 

Prof. Pierto Cicuta, University of Cambridge, UK.

Prof. Paula J Booth, Kings College London, UK.  

Dr. Nick Brooks, Imperial College London, UK. 

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PAST MENTORS

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Prof. V A Raghunathan, Raman Research Institute, India

Prof. Oscar Ces, Imperial College London, UK

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